On the Week 11 NFL slate, we have the Saints (-1) as the best against-the-spread bet on the card. See below for more suggestions on point spreads and totals, including parlay opportunities.

NFL Picks Against the Spread – Week 11

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Pick: Saints -1 vs. Browns

• Matchup: Cleveland Browns at New Orleans Saints
• Projected Winner & Margin: Saints by 6.9 points (Bet on this game at BetMGM)
• Spread: Saints -1
• Time: 1 p.m. ET
• Date: Nov. 17
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Chargers -1.5 vs. Bengals

• Matchup: Cincinnati Bengals at Los Angeles Chargers
• Projected Winner & Margin: Chargers by 10.7 points (Bet on this game at BetMGM)
• Spread: Chargers -1.5
• Time: 8:20 p.m. ET
• Date: Nov. 17
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Broncos -2.5 vs. Falcons

• Matchup: Atlanta Falcons at Denver Broncos
• Projected Winner & Margin: Broncos by 5.3 points (Bet on this game at BetMGM)
• Spread: Broncos -2.5
• Time: 4:05 p.m. ET
• Date: Nov. 17
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Bills -2.5 vs. Chiefs

• Matchup: Kansas City Chiefs at Buffalo Bills
• Projected Winner & Margin: Bills by 3.7 points (Bet on this game at BetMGM)
• Spread: Bills -2.5
• Time: 4:25 p.m. ET
• Date: Nov. 17
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Steelers +3 vs. Ravens

• Matchup: Baltimore Ravens at Pittsburgh Steelers
• Projected Winner & Margin: Steelers by 2.2 points (Bet on this game at BetMGM)
• Spread: Ravens -3
• Time: 1 p.m. ET
• Date: Nov. 17
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Eagles -3.5 vs. Commanders

• Matchup: Washington Commanders at Philadelphia Eagles
• Projected Winner & Margin: Eagles by 5.6 points (Bet on this game at BetMGM)
• Spread: Eagles -3.5
• Time: 8:15 p.m. ET
• Date: Nov. 14
• TV Channel: Amazon Prime Video
• Live Stream: Watch this game on Prime Video (Regional restrictions may apply)

Pick: Colts +4 vs. Jets

• Matchup: Indianapolis Colts at New York Jets
• Projected Winner & Margin: Jets by 0.2 points (Bet on this game at BetMGM)
• Spread: Jets -4
• Time: 1 p.m. ET
• Date: Nov. 17
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Patriots +5 vs. Rams

• Matchup: Los Angeles Rams at New England Patriots
• Projected Winner & Margin: Rams by 4.4 points (Bet on this game at BetMGM)
• Spread: Rams -5
• Time: 1 p.m. ET
• Date: Nov. 17
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Vikings -6 vs. Titans

• Matchup: Minnesota Vikings at Tennessee Titans
• Projected Winner & Margin: Vikings by 15.1 points (Bet on this game at BetMGM)
• Spread: Vikings -6
• Time: 1 p.m. ET
• Date: Nov. 17
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Packers -6.5 vs. Bears

• Matchup: Green Bay Packers at Chicago Bears
• Projected Winner & Margin: Packers by 8.4 points (Bet on this game at BetMGM)
• Spread: Packers -6.5
• Time: 1 p.m. ET
• Date: Nov. 17
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: 49ers -6.5 vs. Seahawks

• Matchup: Seattle Seahawks at San Francisco 49ers
• Projected Winner & Margin: 49ers by 7.6 points (Bet on this game at BetMGM)
• Spread: 49ers -6.5
• Time: 4:05 p.m. ET
• Date: Nov. 17
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Cowboys +7.5 vs. Texans

• Matchup: Houston Texans at Dallas Cowboys
• Projected Winner & Margin: Texans by 7.4 points (Bet on this game at BetMGM)
• Spread: Texans -7.5
• Time: 8:15 p.m. ET
• Date: Nov. 18
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Raiders +8 vs. Dolphins

• Matchup: Las Vegas Raiders at Miami Dolphins
• Projected Winner & Margin: Dolphins by 5.1 points (Bet on this game at BetMGM)
• Spread: Dolphins -8
• Time: 1 p.m. ET
• Date: Nov. 17
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Lions -13 vs. Jaguars

• Matchup: Jacksonville Jaguars at Detroit Lions
• Projected Winner & Margin: Lions by 23.6 points (Bet on this game at BetMGM)
• Spread: Lions -13
• Time: 1 p.m. ET
• Date: Nov. 17
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

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